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Transcription Factor-Mediated Generation of Dopaminergic Neurons from Human iPSCs—A Comparison of Methods

Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been generated from human-skin-cell-derived induced pluripot...

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Wedi'i Gadw mewn:
Prif Awduron: Kirstin O. McDonald, Nikita M. A. Lyons, Luca K. C. Gray, Janet B. Xu, Lucia Schoderboeck, Stephanie M. Hughes, Indranil Basak
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2024-06-01
Cyfres:Cells
Pynciau:
human-induced pluripotent stem cells
dopaminergic neurons
transcription factors
ASCL1
LMX1A
NURR1
Mynediad Ar-lein:https://www.mdpi.com/2073-4409/13/12/1016
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