LysG-driven transcriptional network rewiring underlies lineage-specific phenotypes in Mycobacterium tuberculosis

Abstract The Mycobacterium tuberculosis complex (MTBC) includes ten human-adapted lineages with varying geography and pathogenicity. Lineage 1 (L1) shows low virulence while Lineage 2 (L2) is hyper-virulent, more transmissible, and associated with drug-resistance. We performed comparative analyses i...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Amir Banaei-Esfahani, Sonia Borrell, Andrej Trauner, Sebastian M. Gygli, Tige R. Rustad, Julia Feldmann, Ludovic C. Gillet, Olga T. Schubert, Christian Beisel, David R. Sherman, Ruedi Aebersold, Sebastien Gagneux, Ben C. Collins
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-03-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-026-70539-4
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!