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LysG-driven transcriptional network rewiring underlies lineage-specific phenotypes in Mycobacterium tuberculosis

Abstract The Mycobacterium tuberculosis complex (MTBC) includes ten human-adapted lineages with varying geography and pathogenicity. Lineage 1 (L1) shows low virulence while Lineage 2 (L2) is hyper-virulent, more transmissible, and associated with drug-resistance. We performed comparative analyses i...

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Bibliografski detalji
Glavni autori: Amir Banaei-Esfahani, Sonia Borrell, Andrej Trauner, Sebastian M. Gygli, Tige R. Rustad, Julia Feldmann, Ludovic C. Gillet, Olga T. Schubert, Christian Beisel, David R. Sherman, Ruedi Aebersold, Sebastien Gagneux, Ben C. Collins
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2026-03-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-026-70539-4
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