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Association of metformin with risk of digestive tract cancers from a drug target mendelian randomization and cell experiments

Abstract Background Digestive tract cancers account for a significant proportion of the global cancer burden, and their prevention and treatment pose a worldwide challenge. Metformin, as a first-line treatment for diabetes, offers advantages such as high safety and affordability. Previous research h...

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Principais autores: Yifei Wang, Xirong Cao, Jie Ren, Rui Chen, Xing Zhang, Chang Liu, Yifan Jia, Ting Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2025-05-01
coleção:Discover Oncology
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Acesso em linha:https://doi.org/10.1007/s12672-025-02729-3
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