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Metformin Therapeutic Targets for Aortic Aneurysms: A Mendelian Randomization and Colocalization Study

Background: Identifying effective pharmacological interventions to prevent the progressive enlargement and rupture of aortic aneurysms (AAs) is critical. Previous studies have suggested links between metformin use and a decreased incidence of AAs. In this study, we employed Mendelian randomization (...

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Principais autores: Jingwen Liu, Mingyuan Xu, Bin Ni, Zhaohua Zhang, Xixi Gao, Dingkai Zhang, Liang Yang, Zhidong Ye, Jianyan Wen, Peng Liu
Formato: Artigo
Idioma:Inglês
Publicado em: IMR Press 2024-03-01
coleção:Reviews in Cardiovascular Medicine
Assuntos:
aortic aneurysm
colocalization
metformin
mendelian randomization
Acesso em linha:https://www.imrpress.com/journal/RCM/25/3/10.31083/j.rcm2503089
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