Safety and feasibility of hyperkalemic cardioplegia with diazoxide in cardiac surgery: The Cardioplegia with Diazoxide in Cardiac Surgery TrialCentral MessagePerspective

Background: We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery. These translational findings supported this first-in-human Phase I safet...

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Bibliografische gegevens

Hoofdauteurs:	AlleaBelle Bradshaw, MD, Jessica B. Briscoe, MD, Lisa Fornaresio, PhD, Zyriah Robinson, BS, Michelle Carvajal Villalba, MD, Shivani Shirodkar, MBBS, MPH, Hamza Aziz, MD, Jennifer S. Lawton, MD
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2026-04-01
Reeks:	JTCVS Open
Onderwerpen:	diazoxide cardioprotection KATP channel
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2666273626001129
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