Safety and feasibility of hyperkalemic cardioplegia with diazoxide in cardiac surgery: The Cardioplegia with Diazoxide in Cardiac Surgery TrialCentral MessagePerspective

Background: We have demonstrated cardioprotection by the adenosine triphosphate–sensitive potassium (KATP) channel opener diazoxide in multiple animal models in an effort to reduce myocardial stunning following cardiac surgery. These translational findings supported this first-in-human Phase I safet...

Popoln opis

Bibliografske podrobnosti

Principais autores:	AlleaBelle Bradshaw, MD, Jessica B. Briscoe, MD, Lisa Fornaresio, PhD, Zyriah Robinson, BS, Michelle Carvajal Villalba, MD, Shivani Shirodkar, MBBS, MPH, Hamza Aziz, MD, Jennifer S. Lawton, MD
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-04-01
Serija:	JTCVS Open
Teme:	diazoxide cardioprotection KATP channel
Online dostop:	http://www.sciencedirect.com/science/article/pii/S2666273626001129
Oznake:	Označite Brez oznak, prvi označite!