Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes
This study provides evidence that human topoisomerase IIIα (TOP3A) is closely associated with active replisomes. The authors uncover TOP3A DNA cleavage complexes (TOP3Accs) repair mechanisms to ensure normal DNA replication and genome integrity.
Gardado en:
| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2023-04-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-023-37498-6 |
| Tags: |
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