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Novel Sulfoxides Facilitate GC-Rich Template Amplification

Certain organic solvents, such as DMSO and betaine, have been reported to enhance PCR amplification, particularly for hard-to-amplify high-GC templates. As a result of extensive structure-activity studies between two groups of compounds—amides and sulfones—we have recently discovered several other p...

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Bibliografiske detaljer
Principais autores: Raj Chakrabarti, Clarence E. Schutt
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2002-04-01
Serier:BioTechniques
Online adgang:https://www.future-science.com/doi/10.2144/02324rr04
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