Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism
Inhibition of the Alzheimer associated γ-secretase impairs the regulation of cellular lipid droplet homeostasis. Presenilins (PS) are the catalytic components of γ-secretase complexes that mediate intramembrane proteolysis. Mutations in the PS genes are a major cause of familial early-onset Alzheime...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Life Science Alliance LLC
2020-06-01
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| Sarja: | Life Science Alliance |
| Linkit: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900521 |
| Tagit: |
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