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Epimutations, Inheritance and Causes of Aberrant DNA Methylation in Cancer

<p>Abstract</p> <p>Epigenetic aberrations such as global hypomethylation and gene-specific hypermethylation are key events that underlie tumour development. Such scenarios are brought about by the loss of control of methylation patterns which typically are reversed in neoplasia in comparison to norm...

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Bibliografische gegevens
Hoofdauteurs: Mossman David, Scott Rodney J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2006-05-01
Reeks:Hereditary Cancer in Clinical Practice
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Online toegang:http://www.hccpjournal.com/content/4/2/75
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