Hypoxia-inducible factors in the immunometabolism of metabolic dysfunction-associated steatotic liver disease (MASLD): molecular mechanisms and therapeutic implications

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a predominant cause of liver disease globally, primarily due to the rising prevalence of metabolic disorders, including obesity and diabetes. The advancement of MASLD from simple steatosis to metabolic dysfunction-associated...

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Principais autores:	Yinan Zhao, Yige Wang, Faying Li, Guoying Yu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-02-01
Series:	Frontiers in Physiology
Assuntos:	fibrosis hypoxia hypoxia-inducible factors immunometabolism lipid metabolism liver inflammation
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fphys.2026.1779019/full
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