Development of a Cyclodextrin-Based Mucoadhesive-Thermosensitive In Situ Gel for Clonazepam Intranasal Delivery

A thermosensitive, mucoadhesive in-situ gel for clonazepam (CLZ) intranasal delivery was developed, which aimed to achieve prolonged in-situ residence and controlled drug release, overcoming problems associated with its oral or parenteral administration. Poloxamer was selected as a thermosensitive p...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Marzia Cirri, Francesca Maestrelli, Giulia Nerli, Natascia Mennini, Mario D’Ambrosio, Cristina Luceri, Paola Angela Mura
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-06-01
Serija:	Pharmaceutics
Teme:	clonazepam in situ nasal gel poloxamer mucoadhesive polymers randomly methylated β-Cyclodextrin permeability
Online dostop:	https://www.mdpi.com/1999-4923/13/7/969
Oznake:	Označite Brez oznak, prvi označite!