PTGES3 proteolysis using the liposomal peptide-PROTAC approach

Abstract Background Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, and the lack of effective biomarkers for early detection leads to poor therapeutic outcomes. Prostaglandin E Synthase 3 (PTGES3) is a putative prognostic marker in many solid tumors; however,...

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主要な著者:	Shiwei Liu, Fukang Yuan, Hui Dong, Jiaqi Zhang, Xinyu Mao, Yangsui Liu, Huansong Li
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-12-01
シリーズ:	Biology Direct
主題:	PTGES3 Peptide proteolysis-targeting chimera Liposome Hepatocellular Carcinoma
オンライン･アクセス:	https://doi.org/10.1186/s13062-024-00580-0
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