Fragment-based discovery of novel small molecule targeting human BAG3
Bcl-2-associated athanogene 3 (BAG3) is a multifunctional co-chaperone protein that regulates apoptosis, autophagy, and proteostasis through interactions with HSP70 and other partners. Overexpression of BAG3 contributes to tumor cell survival, metastasis, and chemotherapy resistance, making it an ap...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2026-04-01
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| Seri Bilgileri: | European Journal of Medicinal Chemistry Reports |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2772417426000063 |
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