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Fascin induces melanoma tumorigenesis and stemness through regulating the Hippo pathway

Abstract Background Fascin is a F-actin bundling protein and its overexpression is correlated with poor prognosis and increases metastatic potential in a number of cancers. But underlying function and mechanism of fascin on tumorigenesis in melanoma remain elusive. Methods The melanoma cell lines WM...

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Bibliografische Detailangaben
Hauptverfasser: Jiaxin Kang, Jian Wang, Zhuang Yao, Yuanzhao Hu, Shijie Ma, Qin Fan, Feng Gao, Yan Sun, Jianwei Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-07-01
Schriftenreihe:Cell Communication and Signaling
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Online-Zugang:http://link.springer.com/article/10.1186/s12964-018-0250-1
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