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Bcl-2 dependent modulation of Hippo pathway in cancer cells

Abstract Introduction Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in regulating apoptosis and resistance to therapy in cancer cells, but also for their non-canonical functions, mainly includi...

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Principais autores: Simona D’Aguanno, Matteo Brignone, Stefano Scalera, Martina Chiacchiarini, Marta Di Martile, Elisabetta Valentini, Francesca De Nicola, Alessia Ricci, Fabio Pelle, Claudio Botti, Marcello Maugeri-Saccà, Donatella Del Bufalo
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-05-01
Colecção:Cell Communication and Signaling
Assuntos:
Bcl-2
Melanoma
Breast cancer
Hippo Pathway
Acesso em linha:https://doi.org/10.1186/s12964-024-01647-1
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