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Nilotinib Effects in Parkinson’s disease and Dementia with Lewy bodies

Background : We evaluated the effects of low doses of the tyrosine kinase Abelson (Abl) inhibitor Nilotinib, on safety and pharmacokinetics in Parkinson’s disease dementia or dementia with Lewy bodies. Objectives : The primary outcomes of this study were safety and tolerability; pharmacokinetics and...

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Autors principals: Fernando Pagan, Michaeline Hebron, Ellen H. Valadez, Yasar Torres-Yaghi, Xu Huang, Reversa R. Mills, Barbara M. Wilmarth, Hellen Howard, Connell Dunn, Alexis Carlson, Abigail Lawler, Sean L. Rogers, Ramsey A. Falconer, Jaeil Ahn, Zhaoxia Li, Charbel Moussa
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publishing 2016-08-01
Col·lecció:Journal of Parkinson’s Disease
Accés en línia:https://doi.org/10.3233/JPD-160867
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