3,4-Difluorobenzocurcumin Inhibits Vegfc-Vegfr3-Erk Signalling to Block Developmental Lymphangiogenesis in Zebrafish

Lymphangiogenesis, the formation of new lymphatic vessels from pre-existing vasculature, plays critical roles in disease, including in cancer metastasis and chronic inflammation. Preclinical and recent clinical studies have now demonstrated therapeutic utility for several anti-lymphangiogenic agents...

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Autors principals:	Kazuhide S. Okuda, Mei Fong Ng, Nur Faizah Ruslan, Neil I. Bower, Dedrick Soon Seng Song, Huijun Chen, Sungmin Baek, Philip S. Crosier, Katarzyna Koltowska, Jonathan W. Astin, Pei Jean Tan, Benjamin M. Hogan, Vyomesh Patel
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-06-01
Col·lecció:	Pharmaceuticals
Matèries:	3,4-Difluorobenzocurcumin zebrafish lymphatic Vegfc Vegfr3 Erk
Accés en línia:	https://www.mdpi.com/1424-8247/14/7/614
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