LMNA R482L mutation causes impairments in C2C12 myoblasts subpopulations, alterations in metabolic reprogramming during differentiation, and oxidative stress

Abstract LMNA mutations causing classical familial partial lipodystrophy of Dunnigan type (FPLD2) usually affect residue R482. FPLD is a severe metabolic disorder that often leads to cardiovascular and skeletal muscle complications. How LMNA mutations affect the functional properties of skeletal mus...

Descrición completa

Detalles Bibliográficos

Principais autores:	Oksana A. Ivanova, Alexander V. Predeus, Margarita Y. Sorokina, Elena V. Ignatieva, Danila E. Bobkov, Kseniia S. Sukhareva, Anna A. Kostareva, Renata I. Dmitrieva
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2025-02-01
Series:	Scientific Reports
Acceso en liña:	https://doi.org/10.1038/s41598-025-88219-6
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!