LMNA R482L mutation causes impairments in C2C12 myoblasts subpopulations, alterations in metabolic reprogramming during differentiation, and oxidative stress

Abstract LMNA mutations causing classical familial partial lipodystrophy of Dunnigan type (FPLD2) usually affect residue R482. FPLD is a severe metabolic disorder that often leads to cardiovascular and skeletal muscle complications. How LMNA mutations affect the functional properties of skeletal mus...

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Egile Nagusiak:	Oksana A. Ivanova, Alexander V. Predeus, Margarita Y. Sorokina, Elena V. Ignatieva, Danila E. Bobkov, Kseniia S. Sukhareva, Anna A. Kostareva, Renata I. Dmitrieva
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2025-02-01
Saila:	Scientific Reports
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-025-88219-6
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