Synthesis and Biological Evaluation of Coumarin-Linked 4-Anilinomethyl-1,2,3-Triazoles as Potent Inhibitors of Carbonic Anhydrases IX and XIII Involved in Tumorigenesis
A series of coumarin-linked 4-anilinomethyl-1,2,3-triazoles (<b>6a</b>–<b>t</b>) was synthesized via a molecular hybridization approach, through carbon C-6 of the coumarin moiety. The synthesized compounds were evaluated for their inhibition of carbonic anhydrase (CA) isoforms I, II, IX and XIII. CA...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
MDPI AG
2021-04-01
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| Seria: | Metabolites |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.mdpi.com/2218-1989/11/4/225 |
| Etykiety: |
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