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The impact of trauma relevant concentrations of prostaglandin E2 on the anti-microbial activity of the innate immune system

BackgroundThe mechanisms underlying the state of systemic immune suppression that develops following major trauma are poorly understood. A post-injury increase in circulating levels of prostaglandin E2 (PGE2) has been proposed as a contributory factor, yet few studies have addressed how trauma influ...

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Hlavní autoři: Thomas Nicholson, Antonio Belli, Janet M. Lord, Jon Hazeldine
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-10-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1401185/full
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