Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy

<p>Abstract</p> <p>Background</p> <p>It has been previously shown that enveloped viruses can be inactivated using aryl azides, such as 1-iodo-5-azidonaphthalene (INA), plus UVA irradiation with preservation of surface epitopes in the inactivated virus preparations. Prolonged UVA irradiation in the p...

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Auteurs principaux:	Belanger Julie M, Raviv Yossef, Viard Mathias, Baxa Ulrich, Blumenthal Robert
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2012-03-01
Collection:	Virology Journal
Sujets:	Influenza virus Detergent Detergent resistance Hemagglutinin Triton Vaccine Inactivation Human immunodeficiency virus HIV-1 Orthogonal
Accès en ligne:	http://www.virologyj.com/content/9/1/72
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