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Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy

<p>Abstract</p> <p>Background</p> <p>It has been previously shown that enveloped viruses can be inactivated using aryl azides, such as 1-iodo-5-azidonaphthalene (INA), plus UVA irradiation with preservation of surface epitopes in the inactivated virus preparations. Prolonged UVA irradiation in the p...

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Principais autores: Belanger Julie M, Raviv Yossef, Viard Mathias, Baxa Ulrich, Blumenthal Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-03-01
coleção:Virology Journal
Assuntos:
Influenza virus
Detergent
Detergent resistance
Hemagglutinin
Triton
Vaccine
Inactivation
Human immunodeficiency virus
HIV-1
Orthogonal
Acesso em linha:http://www.virologyj.com/content/9/1/72
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