Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene

Summary: Organoid technology provides the possibility of culturing patient-derived colon tissue and colorectal cancers (CRCs) while maintaining all functional and phenotypic characteristics. Labeling stem cells, especially in normal and benign tumor organoids of human colon, is challenging and there...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Koen C. Oost, Lisa van Voorthuijsen, Arianna Fumagalli, Rik G.H. Lindeboom, Joep Sprangers, Manja Omerzu, Maria J. Rodriguez-Colman, Maria C. Heinz, Ingrid Verlaan-Klink, Madelon M. Maurice, Boudewijn M.T. Burgering, Jacco van Rheenen, Michiel Vermeulen, Hugo J.G. Snippert
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2018-02-01
Edice:	Cell Reports
Témata:	organoids intestine colorectal cancer stem cells LGR5 ASCL2
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124718300652
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!