Physiological medium and 3-hydroxybutyrate modulate autophagy-linked organelle remodeling in human external urethral sphincter myoblasts

Abstract Autophagy-linked organelle remodeling is essential for skeletal muscle differentiation and is closely linked to the metabolic environment. The ketone body 3-hydroxybutyrate (3HB) serves as an alternative energy substrate and signaling molecule that modulates organelle function and myogenic...

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Detalhes bibliográficos

Principais autores:	Hironori Kai, Shinro Hata, Noriko Hamamatsu, Ryoko Shiraishi, Toshitaka Shin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-03-01
coleção:	Scientific Reports
Assuntos:	Autophagy stress urinary incontinence external urethral sphincter 3-hydroxybutyrate physiological medium
Acesso em linha:	https://doi.org/10.1038/s41598-026-43453-4
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