Physiological medium and 3-hydroxybutyrate modulate autophagy-linked organelle remodeling in human external urethral sphincter myoblasts

Abstract Autophagy-linked organelle remodeling is essential for skeletal muscle differentiation and is closely linked to the metabolic environment. The ketone body 3-hydroxybutyrate (3HB) serves as an alternative energy substrate and signaling molecule that modulates organelle function and myogenic...

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Principais autores:	Hironori Kai, Shinro Hata, Noriko Hamamatsu, Ryoko Shiraishi, Toshitaka Shin
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2026-03-01
Serija:	Scientific Reports
Teme:	Autophagy stress urinary incontinence external urethral sphincter 3-hydroxybutyrate physiological medium
Online dostop:	https://doi.org/10.1038/s41598-026-43453-4
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