Inhibition of adenovirus replication by CRISPR-Cas9-mediated targeting of the viral E1A gene
DNA-targeting CRISPR-Cas systems are able to cleave dsDNA in mammalian cells. Accordingly, they have been employed to target the genomes of dsDNA viruses, mostly when present in cells in a non-replicative state with low copy numbers. However, the sheer amount of viral DNA produced within a very shor...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2023-06-01
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| Seri Bilgileri: | Molecular Therapy: Nucleic Acids |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2162253123000537 |
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