A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis
Abstract Background Our study aims to investigate an intrinsic link underlying sex hormone-binding globulin (SHBG) and rheumatoid arthritis (RA), which remains inconclusive in observational settings. Methods Summary statistics were collected from the largest GWAS(s) on SHBG adjusted for BMI (SHBGadj...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2023-08-01
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| Serier: | Human Genomics |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s40246-023-00528-x |
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