RETRACTED ARTICLE: Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

Abstract Neurodegenerative disorders such as Parkinson’s Disease (PD), PD dementia (PDD) and Dementia with Lewy bodies (DLB) are characterized by progressive accumulation of α-synuclein (α-syn) in neurons. Recent studies have proposed that neuron-to-neuron propagation of α-syn plays a role in the pa...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Brian Spencer, Elvira Valera, Edward Rockenstein, Cassia Overk, Michael Mante, Anthony Adame, Wagner Zago, Peter Seubert, Robin Barbour, Dale Schenk, Dora Games, Robert A. Rissman, Eliezer Masliah
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2017-01-01
Rangatū:	Acta Neuropathologica Communications
Ngā marau:	α-synuclein Animal model Axonal transport Immunization Synucleinopathy
Urunga tuihono:	https://doi.org/10.1186/s40478-016-0410-8
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!