RETRACTED ARTICLE: Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

Abstract Neurodegenerative disorders such as Parkinson’s Disease (PD), PD dementia (PDD) and Dementia with Lewy bodies (DLB) are characterized by progressive accumulation of α-synuclein (α-syn) in neurons. Recent studies have proposed that neuron-to-neuron propagation of α-syn plays a role in the pa...

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主要な著者:	Brian Spencer, Elvira Valera, Edward Rockenstein, Cassia Overk, Michael Mante, Anthony Adame, Wagner Zago, Peter Seubert, Robin Barbour, Dale Schenk, Dora Games, Robert A. Rissman, Eliezer Masliah
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2017-01-01
シリーズ:	Acta Neuropathologica Communications
主題:	α-synuclein Animal model Axonal transport Immunization Synucleinopathy
オンライン･アクセス:	https://doi.org/10.1186/s40478-016-0410-8
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