Cost-Effective Method for Full-Length Sequencing of Monoclonal Antibodies from Hybridoma Cells

Background: Monoclonal antibodies play an important role in therapeutic and analytical applications. For recombinant expression, the coding sequences of the variable regions of the heavy and light chains are required. In addition, cloning antibody sequences, including constant regions, reduces the i...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Sarah Döring, Georg Tscheuschner, Sabine Flemig, Michael G. Weller, Zoltán Konthur
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-08-01
Цуврал:	Antibodies
Нөхцлүүд:	full-length antibody sequencing hybridoma cell loss MALDI-TOF MS immunoglobulin isotyping RNA Illumina sequencing
Онлайн хандалт:	https://www.mdpi.com/2073-4468/14/3/72
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!