Cost-Effective Method for Full-Length Sequencing of Monoclonal Antibodies from Hybridoma Cells

Background: Monoclonal antibodies play an important role in therapeutic and analytical applications. For recombinant expression, the coding sequences of the variable regions of the heavy and light chains are required. In addition, cloning antibody sequences, including constant regions, reduces the i...

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Hlavní autoři:	Sarah Döring, Georg Tscheuschner, Sabine Flemig, Michael G. Weller, Zoltán Konthur
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-08-01
Edice:	Antibodies
Témata:	full-length antibody sequencing hybridoma cell loss MALDI-TOF MS immunoglobulin isotyping RNA Illumina sequencing
On-line přístup:	https://www.mdpi.com/2073-4468/14/3/72
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