GDI2 protein: research progress and its mechanisms in diseases

GDP dissociation inhibitor 2 (GDI2), also termed RabGDIβ, is an evolutionarily conserved Rab GDP dissociation inhibitor that is broadly expressed across species and is required for fundamental cellular functions. Mechanistically, GDI2 controls the cycling of Rab small GTPases between membranes and t...

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Hlavní autoři:	Changjian He, Tian He, Zan Zuo, Chao Yang, Yudan Zhang, Guanqi Su, Yunjiao Gong, Ping Wan, Wen Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	GDP dissociation inhibitor 2 (GDI2) rab GTPases endocrine metabolism cancer-related regulation neurodegenerative diseases infection immunity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1848213/full
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