GDI2 protein: research progress and its mechanisms in diseases

GDP dissociation inhibitor 2 (GDI2), also termed RabGDIβ, is an evolutionarily conserved Rab GDP dissociation inhibitor that is broadly expressed across species and is required for fundamental cellular functions. Mechanistically, GDI2 controls the cycling of Rab small GTPases between membranes and t...

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Autores principales:	Changjian He, Tian He, Zan Zuo, Chao Yang, Yudan Zhang, Guanqi Su, Yunjiao Gong, Ping Wan, Wen Zhang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-06-01
Colección:	Frontiers in Cell and Developmental Biology
Materias:	GDP dissociation inhibitor 2 (GDI2) rab GTPases endocrine metabolism cancer-related regulation neurodegenerative diseases infection immunity
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fcell.2026.1848213/full
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