Codi QR

TGF-β/SMAD signaling maintains nucleus pulposus stem cell quiescence to protect against oxidative injury in intervertebral disc degeneration

Abstract Background Intervertebral disc degeneration (IVDD) is characterized by progressive nucleus pulposus cell loss and extracellular matrix degradation, in which persistent oxidative stress plays a critical pathogenic role. Transplantation of nucleus pulposus–derived stem cells (NPSCs) is a prom...

Descripció completa

Guardat en:
Autors principals: Qi Chen, Xiaolong Chen, Qu Yang, Xinxin Miao, Jinghong Yuan, Shuihua Ding, Rui Ding, Shenghao Cai, Bin Li, Xigao Cheng
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-04-01
Col·lecció:Stem Cell Research & Therapy
Matèries:
Nucleus pulposus stem cells
Quiescence
IVDD
Oxidative stress
Apoptosis
P53
Accés en línia:https://doi.org/10.1186/s13287-026-05031-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars