Dexmedetomidine combined with propofol attenuates myocardial ischemia/reperfusion injury by activating the AMPK signaling pathway

Objective: Myocardial ischemia/reperfusion (MI/R) injury is a major cause of cardiac tissue damage, with high disability and death rates. Although both dexmedetomidine (Dex) and propofol (PPF) have been indicated to alleviate MI/R injury in rat models, the effects of the combined use of these two dr...

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Bibliografische Detailangaben

Hauptverfasser:	Ke Yang, Yinhong Ma, Chunmei Xie, Lixian He, Haoxing Zhao, Zheng Dai, Xiaoqi Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-11-01
Schriftenreihe:	Heliyon
Schlagworte:	Myocardial ischemia/reperfusion injury Dexmedetomidine Propofol AMPK signaling pathway Apoptosis Autophagy
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405844023092629
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