Distinct genome-wide DNA methylation and gene expression signatures in classical monocytes from African American patients with systemic sclerosis

Abstract Background Systemic sclerosis (SSc) is a multisystem autoimmune disorder that has an unclear etiology and disproportionately affects women and African Americans. Despite this, African Americans are dramatically underrepresented in SSc research. Additionally, monocytes show heightened activa...

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Detalhes bibliográficos

Principais autores:	Peter C. Allen, Sarah Smith, Robert C. Wilson, Jena R. Wirth, Nathan H. Wilson, DeAnna Baker Frost, Jonathan Flume, Gary S. Gilkeson, Melissa A. Cunningham, Carl D. Langefeld, Devin M. Absher, Paula S. Ramos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-02-01
coleção:	Clinical Epigenetics
Assuntos:	Scleroderma Autoimmune Black Epigenenomic Transcriptomic Blood
Acesso em linha:	https://doi.org/10.1186/s13148-023-01445-5
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