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An altered transcriptome underlies cln5-deficiency phenotypes in Dictyostelium discoideum

Mutations in CLN5 cause a subtype of neuronal ceroid lipofuscinosis (NCL) called CLN5 disease. The NCLs, commonly referred to as Batten disease, are a family of neurodegenerative lysosomal storage diseases that affect all ages and ethnicities globally. Previous research showed that CLN5 participates...

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Bibliografski detalji
Glavni autori: William D. Kim, Robert J. Huber
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-11-01
Serija:Frontiers in Genetics
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fgene.2022.1045738/full
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