Valproate regulates inositol synthesis by reducing expression of myo-inositol-3-phosphate synthase
Abstract Inositol depletion is a hypothesized mechanism of action of mood stabilization drugs used in the treatment of bipolar disorder. It was previously reported that the mood stabilizer valproate (VPA) increased phosphorylation of myo-inositol-3-phosphate synthases (MIPS), the rate limiting enzym...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2023-09-01
|
| Colección: | Scientific Reports |
| Acceso en línea: | https://doi.org/10.1038/s41598-023-41936-2 |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|