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Increased life span due to calorie restriction in respiratory-deficient yeast.

A model for replicative life span extension by calorie restriction (CR) in yeast has been proposed whereby reduced glucose in the growth medium leads to activation of the NAD+-dependent histone deacetylase Sir2. One mechanism proposed for this putative activation of Sir2 is that CR enhances the rate...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Matt Kaeberlein, Di Hu, Emily O Kerr, Mitsuhiro Tsuchiya, Eric A Westman, Nick Dang, Stanley Fields, Brian K Kennedy
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2005-11-01
Цуврал:PLoS Genetics
Онлайн хандалт:http://europepmc.org/articles/PMC1287956?pdf=render
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