Insights into the Mechanism and Catalysis of Peptide Thioester Synthesis by Alkylselenols Provide a New Tool for Chemical Protein Synthesis

While thiol-based catalysts are widely employed for chemical protein synthesis relying on peptide thioester chemistry, this is less true for selenol-based catalysts whose development is in its infancy. In this study, we compared different selenols derived from the selenocysteamine scaffold for their...

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Ngā kaituhi matua:	Florent Kerdraon, Gemma Bogard, Benoît Snella, Hervé Drobecq, Muriel Pichavant, Vangelis Agouridas, Oleg Melnyk
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2021-03-01
Rangatū:	Molecules
Ngā marau:	peptide thioester alkylselenol catalysis chemical protein synthesis
Urunga tuihono:	https://www.mdpi.com/1420-3049/26/5/1386
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!