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KIF22 regulates mitosis and proliferation of chondrocyte cells

Summary: Point mutations in KIF22 have been linked to spondyloepimetaphyseal dysplasia with joint laxity, type 2 (SEMDJL2). Skeletal features of SEMDJL2 include short stature and joint laxity. Mechanisms underlying these limb abnormalities are unknown. Here in this manuscript, we have investigated t...

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Principais autores: Hiroka Kawaue, Takuma Matsubara, Kenichi Nagano, Aoi Ikedo, Thira Rojasawasthien, Anna Yoshimura, Chihiro Nakatomi, Yuuki Imai, Yoshimitsu Kakuta, William N. Addison, Shoichiro Kokabu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-07-01
Serier:iScience
Fag:
cell biology
Molecular biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224013762
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