Mechanisms of tumor-derived extracellular vesicle-mediated immunometabolic reprogramming and immunotherapeutic resistance

Abstract Background Tumor-derived extracellular vesicles (tEVs) are emerging as pivotal mediators of intercellular communication within the tumor microenvironment (TME). Beyond carrying oncogenic cargo, tEVs dynamically reprogram immune and metabolic networks that shape tumor progression and therape...

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Auteurs principaux:	Hongyue Zeng, Ruiqi Zhang, Xingyao Zhu, Shuqi Shen, Hong Zou
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-01-01
Collection:	Molecular Cancer
Sujets:	Tumor-derived extracellular vesicles Immunometabolic reprogramming Metabolic checkpoints Immune evasion Immunotherapy resistance Artificial intelligence
Accès en ligne:	https://doi.org/10.1186/s12943-025-02556-8
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