Mechanisms of tumor-derived extracellular vesicle-mediated immunometabolic reprogramming and immunotherapeutic resistance

Abstract Background Tumor-derived extracellular vesicles (tEVs) are emerging as pivotal mediators of intercellular communication within the tumor microenvironment (TME). Beyond carrying oncogenic cargo, tEVs dynamically reprogram immune and metabolic networks that shape tumor progression and therape...

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Главные авторы:	Hongyue Zeng, Ruiqi Zhang, Xingyao Zhu, Shuqi Shen, Hong Zou
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-01-01
Серии:	Molecular Cancer
Предметы:	Tumor-derived extracellular vesicles Immunometabolic reprogramming Metabolic checkpoints Immune evasion Immunotherapy resistance Artificial intelligence
Online-ссылка:	https://doi.org/10.1186/s12943-025-02556-8
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