De novo basecalling of RNA modifications at single molecule and nucleotide resolution
Abstract RNA modifications influence RNA function and fate, but detecting them in individual molecules remains challenging for most modifications. Here we present a novel methodology to generate training sets and build modification-aware basecalling models. Using this approach, we develop the m 6 AB...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2025-02-01
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| Seri Bilgileri: | Genome Biology |
| Konular: | |
| Online Erişim: | https://doi.org/10.1186/s13059-025-03498-6 |
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