Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial

Introduction Septic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%. Expression of the triggering receptor expressed on myeloid cells 1 (TREM-1) pathway, measured using...

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Hauptverfasser:	Pierre-François Laterre, Stephan Witte, Jean-Marie Grouin, Simon Lambden, Bruno Francois, Sebastien Gibot, Marc Derive, Aurelie Olivier, Valerie Cuvier, Jean Jacques Garaud, Margarita Salcedo-Magguilli, Mitchell Levy
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMJ Publishing Group 2021-07-01
Schriftenreihe:	BMJ Open
Online-Zugang:	https://bmjopen.bmj.com/content/11/7/e042921.full
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