A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials

Abstract Background Dengue is a neglected tropical disease, for which no therapeutic agents have shown clinical efficacy to date. Clinical trials have used strikingly variable clinical endpoints, which hampers reproducibility and comparability of findings. We investigated a delta modified Sequential...

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Detalhes bibliográficos

Principais autores:	Angela McBride, Nguyen Lam Vuong, Nguyen Van Hao, Nguyen Quang Huy, Ho Quang Chanh, Nguyen Thi Xuan Chau, Nguyen Minh Nguyet, Damien K. Ming, Nguyen Thanh Ngoc, Phung Tran Huy Nhat, Nguyen Thanh Phong, Luong Thi Hue Tai, Phan Vinh Tho, Dinh The Trung, Dong Thi Hoai Tam, Huynh Trung Trieu, Ronald Bertus Geskus, Martin J. Llewelyn, C. Louise Thwaites, Sophie Yacoub
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-09-01
coleção:	BMC Infectious Diseases
Assuntos:	Dengue Shock SOFA Modified SOFA Delta SOFA Clinical trial endpoint
Acesso em linha:	https://doi.org/10.1186/s12879-022-07705-8
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