IL-33 stimulates the anticancer activities of eosinophils through extracellular vesicle-driven reprogramming of tumor cells

Abstract Immune cell-derived extracellular vesicles (EV) affect tumor progression and hold promise for therapeutic applications. Eosinophils are major effectors in Th2-related pathologies recently implied in cancer. Here, we evaluated the anti-tumor activities of eosinophil-derived EV following acti...

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Autori principali:	Adriana Rosa Gambardella, Caterina Antonucci, Cristiana Zanetti, Francesco Noto, Sara Andreone, Davide Vacca, Valentina Pellerito, Chiara Sicignano, Giuseppe Parrottino, Valentina Tirelli, Antonella Tinari, Mario Falchi, Adele De Ninno, Luca Businaro, Stefania Loffredo, Gilda Varricchi, Claudio Tripodo, Claudia Afferni, Isabella Parolini, Fabrizio Mattei, Giovanna Schiavoni
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-07-01
Serie:	Journal of Experimental & Clinical Cancer Research
Soggetti:	Extracellular vesicles Cancer Eosinophils IL-33 Tumor microenvironment Epithelial to mesenchymal transition
Accesso online:	https://doi.org/10.1186/s13046-024-03129-1
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